Though everyone needs to be on alert, few people need to be more alert than others. CNN Medical Analyst Dr. Leana Wen, an emergency physician and professor of health policy and management at the George Washington University Milken Institute School of Public Health says people who are more vulnerable to COVID despite vaccination should be more careful this time.

The expert also says that people who are moderately or severely immunocompromised or with multiple underlying medical conditions may need hospital care and advises these people to have extra precautions. “That includes wearing a high-quality mask (N95, KN95 or KF94) in all indoor public settings, avoiding large crowds and traveling for essential reasons only. Before getting together with other people, they may wish to request that the others are tested for COVID-19,” the expert says.